Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis
M. Dong, V. Kathiresan, M. K. Fenwick, A. T. Torelli, Y. Zhang, J. D. Caranto, B. Dzikovski, A. Sharma, K. M. Lancaster, J. H. Freed, S. E. Ealick, B. M. Hoffman, and H. Lin.
Science 359, 1247-1250 (2018)
Supporting Information
<doi:10.1126/science.aao6595> PMID: 29590073
PMCID: PMC6066404
|
|
Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function
D. Snead, A. L. Lai, R. T. Wragg, D. A. Parisotto, T. F. Ramlall, J. S. Dittman, J. H. Freed, and D. Eliezer.
Front. Mol. Neurosci. 10, 154 (2017)
Supporting Information
<doi:10.3389/fnmol.2017.00154> PMID: 28596722
PMCID: PMC5442187
|
|
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis
M. Dong, M. Horitani, B. Dzikovski, J. H. Freed, S. E. Ealick, B. M. Hoffman, and H. Lin.
J. Am. Chem. Soc. 139, 5680-5683 (2017)
Supporting Information
<doi:10.1021/jacs.7b01712> PMID: 28383907
PMCID: PMC5664936
|
|
Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme
M. Dong, M. Horitani, B. Dzikovski, M. -E. Pandelia, C. Krebs, J. H. Freed, B. M. Hoffman, and H. Lin.
J. Am. Chem. Soc. 138, 9755-9758 (2016)
Supporting Information
<doi:10.1021/jacs.6b04155> PMID: 27465315
PMCID: PMC5068486
|
|
A Fluorimetric Readout Reporting the Kinetics of Nucleotide-Induced Human Ribonucleotide Reductase Oligomerization
Y. Fu, H.-Y. Lin, S. Wisitpitthaya, W.A. Blessing and Y. Aye.
Chembiochem 15 2598-2604 (2014)
<doi:10.1002/cbic.201402368> PMID: 25256246
PMCID: PMC4271543
|
|
Uncoupling of Allosteric and Oligomeric Regulation in a Functional Hybrid Enzyme Constructed from Escherichia coli and Human Ribonucleotide Reductase
Y. Fu, M.J.C. Long, M. Rigney, S. Parvez, W.A. Blessing, Y. Aye.
Biochemistry 52 7050-7059 (2013)
<doi:10.1021/bi400781z> PMID: 24024562
|
|
|